My twin brother called me last week complaining of extremely bad pain and a swollen area in his groin area. From everything he described, I assumed it was a hernia and advised him to go on to the doctor - especially since the pain level was so high. The family doc that he saw told him he needed to be transported to the hospital because she was 99% sure that it was a femoral artery clot and that it was very serious. So they rushed him to the ER. Once there, a doppler was performed and the blood clot was ruled out. They did, however, spot a mass that had a blood supply going to it near the lymph node in his groin area. So they did a couple of cat scans that showed the lymph nodes from his groin all the way to his liver were enlarged and inflamed and also his spleen was enlarged. The ER doc said it could be anything from infection to lymphoma and scheduled a biopsy for the next morning at a hematologist's office. Well, the hematologist only examined him for 5 minutes before determining that it was cat scratch fever. He gave him Keflex to take for 5 days every 6 hours and told him to take motrin/ibuprofen to get the swelling down. Well, it has been five days and my brother went in for his follow up treatment. There has been no improvement what so ever and the antibiotics have made him feel nauseous and run down. But the doctor took all of 5 more minutes to decide to continue the course of treatment we are on and come back in two weeks. Doesn't it seem like if the treatment is not working, then maybe other avenues should be explored? Does anyone have any experience with Cat Scratch Fever and does this seem like teh course the disease usually takes? Any ideas or advice will be greatly appreciated. I hate to see my brother in so much pain! Also, do you think we should get a second opinion? Please help me in any way that you can.