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Old 12-03-2005, 10:21 PM   #6
bucky77
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Unhappy Re: Can Someone Help

thanks for the replys, everyone in here is a lot of help, i'm am still sick after a week now and my doc is slowly rasing my dose of oxycontin, had to go to the er 3 times, they gave me a shot of delodid , helped a little but not much,and about the compounded, the pharmacy said their is filler in it and it is 8 hours relief, they have different capsels for how quick they disolve, and i'm up to 30 mg now and dont have much effect yet, when i had this compounded oxycontin before it only last up to 4 to 6 hours, compared to the real oxy i got 10 to 12 hours relief, and they put stuff in this so it cant be abused, that is a good thing, so no body will steal it, the phar said, i told the pharasist that if some one stole my meds they still could get high, they could just take a hole bunch, bla,bla,bla, anyway, does any know where i can find information on compounded oxy to the real stuff, the phar is making lots of money off this, he is charging the same price. thanks for the replys, and i hope i feel better soon, i went and got a referrel to another sergeon, to see if he can do something for me, i'm only 30, bye for now
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Old 12-04-2005, 08:30 AM   #7
feelbad
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Re: Can Someone Help

I too have a really hard time understanding just how any pharm can actually compound its own oxycontin,really.The dellivery systems are very different than those founf in other meds.I think you are actually getting only some sort of compounded version of oxycodone delievered as oxycodone,you know what I mean?as far as I know,any sort of time release meds that are in a capsule form still have,inside the cap,tiny "beads" that do the time release part of the process.Look at your capsules and see if there are tiny bead looking things or if it is actual powder.or ask the pharmacist directly,just what exactly IS in there.eveything and anything.you DO have the right to know just what they are putting inside these caps.and since it is not listed in a PDR you cannot actually look up this info on your own.I would be willing to bet that you are not getting the actual effects of a true oxycontin type of time release med.It just does not sound possible as far as I know.SHORE??i could be totally wrong here(it has happened in the past,lol) but really i just don't know about this.

you can also go to a different pharm or ask your doc to give you an rx for real oxycontin.just tell himthat whatever it is this pharm is giving you just is not working up to par.this whole thing just doesn't 'sound' right to me,really.you DO have a right to know just what is in there and to ask the pharm just what in the heck actually MAKES the time release delivery actually happen.I am really really curious about just what all this pharm is actually placing into the caps that you are taking.You should be too.you DO have the right to know this just incase he tells you you do not.if you have any problems in obtaining this info,just contact the local chapter of the board of pharmacy for your state.Please let me know just what you find out,K?I hope something starts working here for you soon.Marcia
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Old 12-05-2005, 01:58 PM   #8
Shoreline
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Re: Can Someone Help

Hey Bucky, Aside from whatever the conversion, although meth binds to just about all the receptors tha oxy does, so a switc n that directionis easy compared to the opposite. Methis unique in the receptor activity is creates. Mainlyit blocks the N*** recepotor which controls tolerqane to pain and tolernce to opiates. It's why Ketamine is used n compounding and other crouties, but it had side effects too.

Meth also has more DElta receptor activity than oxy, delta activity doesn't have the eurporic effects like tehe MU reeptor, btut both drugs also ahave MY activity whewre oxy has little Delta receptor activity. These small variations and some other unique qualties of eth make what your experiencing called transitional withdrawal. Even if there was a magic number that gaurenteed euqual relief you would lkely still feel cruddy, so unless you way under dosed on oxy you likely going to feel wrotten any way. 2 weeks sounds about right but you will probably start feelin better around day 10 and by 14 with the right dose of oxy you should be fine.

Compounding LA Oxy can't be that much cheaper. Oxyis expensive but so is compounding. MOst likely they are using Dextromathorphan as an agent to prolong the effectiveness and increase pain tolerance because DXMis also a N*** receptror blocker. OxyContin which is pure oxycodone has a rease desinged by to release at certain points. The drug they are using to extend the coumpounded Oxy I'm guessing is DXM because i have seen it used to create a LA version of hydrocodone. It was need 3-4 times a day, butthat's better then the lucky to get 4 hour meds. Even the name brand OxyC needs to be dosed every 8 hours but Purdue's clam to fame is their 12 hour duration.

Why still compound the meds. Is it a way to fly under the radar as far as prescribing OxyContin or maybe he's done you a favor by adding the DXM to give it some of meths properties so the transition isn't as bad.

As far as convrsion, I haven't seen to many charts that acuretly predict methadone's strength. Most are only god for single dose cmparision beause they don't acount for the 5 days of build up before you steady out. I've swithed meth to morine back t meth and back to morphine and it also ended up at %:1. 120mgs of meth was equal to 600 mgs of mrphine. Oxy is stronger so 3:1 or 4:1 is probably more realistic but docs tend to start on the low side, often the very low side. RAther than self medicate, if you just can't take it, let the doc make the call. I stuck it out knowing there is light at the end of the tunnel if you have confidece your doc will titrate the oxy dose to a level that works. Whether it 3:1 or 5:1 or & 7:1 what works for you is more important.
Good luck, Dave
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Old 12-05-2005, 10:03 PM   #9
Chaddyfriend
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Re: Can Someone Help

why do u even have to get the compunded stuff? why not at least get the generic oxy? why did this pharmacy just automatically compound it? did ur doc ask for it to be componded? If you fill your script at another pharmacy, wouldnt they just give you the generic stuff, which would be better than this compunded crap...just curious...
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Old 12-05-2005, 11:50 PM   #10
conductor
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Re: Can Someone Help

Yes, I have been reading this post PURELY out of interest (and IT IS INTERESTING, ISN'T IT??!!). What is the need for the compounding?

Shoreline, I must admit that you truly have it over me in your understanding of compounding!! After I read your explanations, I need some BT meds to help me!! Please know I'm kidding you. You have such tremendous knowledge about these sorts of things that I'm sure we all possess the appropriate respect for you!

Nonetheless, what is the need for such specifically-dosed compounding of the long-acting (LA) medication in this case?? Whatever the case...we are greatful for those that offer the services of performing such tasks!!

I'm sure we would all like to know WHY the OxyContin (whether it be Brand or generic) needs to be compounded in such an exacting manner IN THIS PARTICULAR CASE. Please let us know how this saga plays out. Honestly, this is running like a Pharmacy School Soap Opera!

Sincerely,
Jon (Conductor)

P.S. I often jest with many of you, but I do take our problems seriously and wholeheartedly maintain the interest of us all!! Thanks, everyone, for your anecdotal (yet utterly vital) information.
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