Which would you pick and why? - Plaquenil or Methotrexate

ToBeFreeToRoam · 02-25-2006, 09:33 PM

Hi Everyone,

I went to my Rheumatologist last week. She is giving me and my gastro. dr. a choice between Plaquenil and Methotrexate. One affects your eyes more and one affects your liver more. That is what my dr. said. So, what do yall know about the side effects of both and the benefits of both? I would appreciate any comments or advice from everyone.

Thanks in advance.

Wannabe

cookingmom · 02-25-2006, 09:48 PM

Hi,

I am on both methotrexate and plaquenil. I have been on plaquenil for over a year and a half and methotrexate since September. I have had no side effects from either one. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes (used to be every 2 weeks). I take these for the arthritis associated with my lupus.

I don't know if this helps you or not. If you have any particular questions, I would be happy to answer them.

I wish you well with this decision and the results.

CTuit · 02-25-2006, 10:11 PM

I would start with the plaquenil. It's much less toxic to the system. The chance of damage to the eyes with plaquenil is extremely slim. Your chances of problems with the methotrexate are a bit larger. Many people do end up with both or a combination of othr drugs.

dazedandconfused1 · 02-25-2006, 11:55 PM

everyone is different with meds i have taken them both a couple years ago on methotrexate i was very sick tired couldnt get off couch my hair was thinning have been on plaquenil a few months now was nauseated first couple days now no side effects ctuit is right i would start out on plaquenil first

ToBeFreeToRoam · 02-26-2006, 01:35 AM

Hi Everyone,

Thanks for you fast information. My Rheumy did say that one started working faster than the other. Do yall know which one? My dr. is giving it me for a rampant case or RA (it just keeps getting worse and worse). She does not want to give me anymore Prednisone and Relafen. I am at my top doses now! So, that is why the change.

Do yall know anything about the costs of either? I have a $5,000. deductible (I am at about $2,500 - $3,000 right now). I would have to pay the copay on the drugs and the total cost of the eye drs. and blood tests and the rheumatologist. Of course I am going to her about every 2 - 3 mo. now, anyway! My hands are just all ate up!!!

Thanks again for your help.

Wannabe