I promised to report back after starting Enbrel. Well, I've been on it since Aug. 3rd. I'm due to take my 3rd injection later today. I'm still nervous about doing it myself so I bring it to work and I have very encouraging co-workers who help me through it. I'm going to start using the auto-injector next month which should be less stressful. I'm still on Prednisone and
Arava along with Enbrel. I, too, have injection site reactions. My doc gave me the first shot so I could see how it was done. That was 2 weeks ago and that leg has a small red hot area. The shot I gave myself last week resulted in a HUGE red hot area. It started as a small black and blue the day after the shot and then 6 days later it's spread. It doesn't really bother me except that I don't think it should be there.
Bottom line - I'm feeling SOOOOOOOO much better!! I'm practically pain free! I haven't felt this good in a very long time. So it's worth a little red patch on my thigh. Good luck to all with whatever medication works for you!