Ive suffered uti's on and off for 15 years, some episodes worse than others. many antibiotics havent worked. Actually the only one that seems to work now, is only prescribed by Consultants in hospitals as its strong, but it does work. Ive had urethral stretches, one worked great i didnt have an infection for a yr, then it came back, and had another stretch, that one hasnt worked. My Consultant says that some people have a missing enzyme which lines the bladder wall, im missing this, and may have to live with this, it is horrible and drags you down, im still going through treatment now