I was taking 3 grain (180mg) of Armour thyroid; now cutting down to 2 (120mg). Took a few weeks on the HC for the thyroid to 'catch up' and I started getting some hyper symptoms. Am not sure why the timing was such. Licorice has no direct affect on thyroid, only indirectly by increasing the half-life of cortisol. Higher cortisol decreases the need for thyroid supplementation. On the other hand, thyroid supplementation increases the need for cortisol. No wonder it's so difficult for us all to get this stuff balanced right!
-Katie