My derm., yes derm., prescribed me Ortho Tri cyclen to help with my acne, however, I decided to go on the generic instead, because in college I can't afford $35 a month. I couldn't tell you if the generic is working at all or not as I started Spiro. at the same time as well. However, my derm. said she seems to think that the generic can make acne worse. I'm hoping to find a generic that helps with acne. Anyway, try the Ortho if you can, and if anyone knows any generics that work good for acne, let me know!