Well after exactly a month I switched from those two topicals to Accutane.. I just got so fed up with my skin, but now I'm experiencing an initial breakout on the accutane, which is a lot worse than what I was experiencing before. Oh man, I kind of wish I would have been patient with Differin and Clindamycin, but Accutane seems a bit more promising for me. Good luck with them though.. That combination seems to work for a lot of people, I just got impatient with the initial breakout. Gah it's always so confusing though...