BYSTOLIC (Nebivolol) - New Hypertensive(Beta Blocker)Medication - Page 8

flowergirl2day · 05-20-2008, 03:05 AM

Hi ACE,

thanks for clarifying your beta blocker prescriptions. Your doctor sounds like someone you can really trust with your health (in spite of his pharmacological preferences). Your normal blood pressure and cholesterol levels speak for themselves. The drugs taken to get such good results are really not important - only the end result is.
How interesting that Toprol had no effect on your triglyceride and HDL levels and Bystolic has altered them! According to my book about cardiovascular drugs, it is mostly the non-selective beta blockers that raise the triglycerides and lower the HDL levels. My personal experience is slightly different. My cholesterol levels were great on a non-selective beta2 blocker. Not so on a beta1 blocker. Perhaps other factors or meds have contributed to the changes. Just goes to show how different we all are. I am glad your cholesterol levels are back to normal!

FG

ACE28 · 05-20-2008, 10:08 AM

Hi Flowergirl,

To clarify -- When I took TOPROL, my HDL dropped on avg.more than 10 points (from about 50 to a low of 39) and my Trigs. increased from about (150 to 250) My doctor could not believe TOPROL could change my numbers so much. When I dropped the TOPROL my HDL jumped to about 47 in three months and my TRIGS around 200.

Taking NIACIN and PRAVACHOL without a beta blocker for the past few years my HDL was always about 52 - 58, and my TOTAL chol. about 200 - 215. While on beta blocker's recently (mainly BYSTOLIC) my TOTAL chol on my last checkup was 266 and my HDL 49.... Though I must admit, I also gained approx 7 pounds since last year, and being my blood test was shortly after EASTER, I may have over-indulged on holiday cakes and sweets etc....

flowergirl2day · 05-22-2008, 02:11 AM

Ace,

I think you mentioned staying on Bystolic. Will you keep taking both Niacin and Pravachol and hope for best? What if they are not strong enough to counteract the effects of your beta blocker? Are you prepared to either try another medication or increase the dose of Niacin and Pravachol? It seems that adjustments to our drug regimens are necessary on an on-going basis, because nothing stays the same for long.

Besides the beta blockers, Hctz also affects the cholesterol levels negatively. I take both of these meds. I'd be very surprised to see any improvement in my cholesterol levels since last tested.
I read that the beta blockers with ISA (intrinsic sympathomimetic activity) such as Sotalol, Acebutolol and Pindolol, do not seem to have adverse effects on the blood lipids. Maybe the low level of agonist activity they exert, in addition to acting as receptor site antagonists, somehow keeps them from interacting with the metabolism of fats. Losing those extra pounds might help a little.

Sugar, NOT fats, is the number one bad guy and causes the most damage to our bodies.

flowergirl

donsabi · 05-26-2008, 12:58 PM

ACE28,
You mentioned you are splitting the 5mg Bystolic and taking 2.5mg. Do you have any problems splitting the pill?

ACE28 · 06-02-2008, 11:29 AM

Quote:

Originally Posted by donsabi

ACE28,
You mentioned you are splitting the 5mg Bystolic and taking 2.5mg. Do you have any problems splitting the pill?

Yes - The 5 mg pill can be split, but it is very inconvenient. The pill shape is triangular with no score line. BYSTOLIC supposed to be offered in a 2.5 mg size in the U.S. in the near future. At least the pill is offered in tablet form as opposed to capsule or gel form......