I, too, noticed that after switching to Aciphex, I have become extremely constipated. I exercise regularly, am not overweight, eat healthy, consume a lot of fiber-rich foods and drink a lot of fluids; but I just realized this problem began soon after taking the Aciphex.
It does the best of the three PPIs I have tried for LPR symptoms, but I have gained a few pounds since starting the Aciphex, too. Depressing.
I'd love to stop taking these meds, but am also worried about the rebound effect I have heard that others have experienced.