Are you on any thyroid meds? Licorice prolongs the life of cortisol, so supposed to be taken in the morning when you need the most cortisol. Increase in cortisol activity may increase the efficacy of your thyroid meds and you may need to adjust the dose downward of your thyroid dose (this is happening to me currently, and one of the symptoms I had of too much thyroid was a faster resting pulse)
-Katie