I have had diarea since I began the Bextra, Arthrotec, Zoloft regime so i don't know which one is causing the diarea. I was just reading on the CBS Homepage about Bextra causing some kind of rash on people with allergy to sulfer. I haven't had any problems with rashes or anything, and I am glad to say have felt much better on these meds than I did on the methotrexate regime. Good luck and let me know how you are doing!!