alcohol, zoloft, and anafranil??

[beachgirl001]

So I have been taking Zoloft for a couple of years now and am on 200 mg. I am in college so I drink on weekends and sometimes during the week. I seem to have a high tolerance. I have been drinking on Zoloft and it doesn't seem to be a problem. Now I am on Anafranil (25mg) and on 200mg of Zoloft.

Has anyone taken this combination and drank alcohol???? Because I tend to drink a couple times a week and I don't know how the alcohol will react with the Zoloft and the Anafranil together.

[zuzu8]

beachgirl,

You've got a potentially potent "cocktail" going here. Both drugs can interact with each other and EACH drug interacts with alcohol.

Anafranil is a tricyclic anti-depressant and Zoloft is an SSRI antidepressant, but you know this already I'm sure.

When you take the 2 together, there is the possibility your blood concentration of anafranil will increase, which of course can lead to unwanted side effects, some serious.

Adding alcohol into the mix is a b-a-ad idea. The pharmaceutical literature for each drug states that Anafranil alone + alcohol can significantly impair your motor skills, especially your driving.

And Zoloft alone+ alcohol can potentiate (i.e. increase) the effects of the Zoloft, again with potentially serious side effects, although you mention that on Zoloft you managed to drink alcohol w/o problem.

But now you've added anafranil into the mix.

I'm sure your doctor is monitoring your dosages of Zoloft and anafranil carefully, but I'd bet my bottom dollar he would seriously warn you about using alcohol while on both of them.

Please be careful.

zuzu xxx