Donsabi,
Stomach upset seems to be the #2 or #3 complaint with Niaspan:
Quote:
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In addition to flushing, other potential side effects of NIASPAN® include rash and stomach upset....(from the KOS ad for Niaspan)
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Taking it with ANY analgesic (which ALL irritate the stomach) seems to be increasing the chances of gastric pain.
Perhaps taking the Niaspan alone with your dinner meal might be easier on the stomach (though I know all cholesterol meds work best at bedtime)...maybe at least with a heavy snack (snack first-then meds.)
Don't ignore the symptom, a peptic ulcer is no fun. (Just for grins, next MD visit have him run a test for H.pylori)