This is my first post. I felt compelled to share with you my success with Spiro. Having had cystic acne on and off for the past 27 years and trying all the mainstream treatments, I began to research new treatments. I first stumbled across Spiro on the HealthBoard. I began to read anything I could find on the Net on Spiro and thought it would be worth a try to discuss this option with my family doctor. Before I could hand her my various internet print-outs, she asked me if I had ever tried Spiro.......Sooooo, to make a long story short, I've been 25 mg for 7 days now. I had previously "sported" about 7-8 cysts on my chin for 3-4 months. As of this date, my chin is about 90% clear. For any of you who haven't entertained the idea, please consider it, after researching the medication and discussing with your doctor. The only side effects I have had are: minor dryness of throat and minor fatigue.....but I can handle that anyday compared to the "way I feel" with cystic acne. By the way, I think this may only be prescribed for females. It has anti-androgen effects and alters the way sebum attaches to the hair follicles in your face. I hope this post helps someone because it this Healthboard has surely helped me!