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Originally Posted by Galsal59
Has anyone had a breast mass with a microlobulated margin that turned out to be benign? Thanks!
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Well, I haven't. But I have found some info that might help you:
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One has to rely upon an array of findings to evaluate solid breast lesions and call it benign or malignant. No characteristics are absolutely specific and it is impossible to distinguish all benign from all solid breast nodules using sonographic criteria. However sonographic criteria to be looked for are :
Shape and margin of the lesion : The shape of a mass can be described as round, oval, lobulated or irregular. Round and oval shapes are suggestive of benign masses. As long as there are fewer than three lobulations, the chances of malignancy is very less. The presence of greater than three lobulations is an indeterminate feature. Irregular shape is suspicious of malignancy. The margin of the lesion reflects the demarcation of the mass with surrounding tissue. It can be smooth, microlobulated, irregular or spiculated. Gentle bilobulated or trilobulated margins are considered smooth. Presence of 2 or 3 gentle smooth, circumscribed and well-encapsulated lobulation strongly favours a benign etiology over cancer. The presence of many small lobulations, that is microlobulations, on surface of solid breast lesion is suspicious of malignancy. Numerous lobulations give the lesion a pleomorphic shape. Microlobulations are frequently associated with angular margins.
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and this one:
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Invasive breast carcinoma
According to the study of Rahbar (3) 2D US features that characterize lesions as malignant are irregular shape (61% malignant), microlobulated (67% malignant), spiculated (67% malignant) and a width-to-depth (anteroposterior dimension) ratio of 1.4 or less (40% malignant). Most of the time the tumor center is characterized by a homogenous echo-poor fibrohyalinosis followed by a dorsal shadowing due to ultrasound energy absorption. The echo-rich margins are the expression of many different tissue components of tumor cells, fibrous strands, fatty tissue and surrounding glandular parenchyma indicating the tumorous growth and infiltration zone. Mammography clearly shows this stellate infiltration pattern with the architectural distortion of the neighbouring structures.
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What I'm finding is that a microlobulated margin of a breast lesion seems to show a two thirds likelihood of malignancy. Benign findings occur about 1/3 of the time. I'm hoping you are in the 1/3 category, sal.
best wishes,
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charli
203/146/146 on the Fat Flush Plan for life and perky to the max.