I've had non-hodgkins lymphoma and the recurrence rate is based on what stage they caught the previous cases in. For instance, I was diagnosed in stage 1 and was told something along the lines that it is 90% curable and 90% that it will not come back. The numbers might not be completely accurate, but it was in the 90% range. The later the stage the lower the percentages become. It also depends on whether or not it spread to the bone marrow and a bone marrow transplant has been done. Another factor would be the grade of the cancer. Research it... go to yahoo and type in lymphoma and you can get lots of info of this nature.
So to answer your question, yes, it can come back more than twice. I was lucky in that I was only in Stage 1 and it was the first time I got it, but even still with that scenario the recurrence rate was not 0%. I was also given that five year rule. If it doesn't come back in 5 yrs that I would be considered cancer free. Still though, having had cancer once, I'm at a higher risk of getting another type of cancer than somebody who has never had cancer before.