I take Allegra D and it used to help a lot, but now it's not working so well. I also started getting allergy shots like a month and a half ago and I'm already seeing great results! I used to be very allergic to cats (I'd get hives, my throat would start to close, my eyes and nose would itch, everything) and now allergy medicine I took would help me with it, but now I hardly have any reaction what so ever.