My dr recently suggested that I use Tylenol + Ibuprofen (alternating between the two) for my OA in my hands (mild to moderate pain, I've been suffering through it for about 10 years now, I'm 36 now). Has anybody else been told to do this? I read about alternating acetaminophen and ibuprofen for a child's fever but not for pain in adults. My dr said it would seem like a lot of pills (it does) but that since I was alternating between the two I would wind up taking less than the recommended amount of each kind of pill while still getting pain relief. If anybody else does this (alternates acetaminophen with an NSAID) please let me know what your experience is. thanks. by the way I had numerous blood tests for Rheumatoid Factor and ANA, sed rate, etc. nothing showed up for RA or any other autoimmune disease thank goodness.