Penny, I have no idea what all medications he is on, or has been on in the past. My brother does not say too much about his conditon. I think that my brother has just come to grips with "this is not something he is going to get over". I understand that this is a disease just like any other. I think that it took my brother awhile to fully understand the disease. I hsave a good friend that also is bipolar-she has been thru shock therapy-and she told me that sometimes she would rather have cancer-at least they know how to treat that-its not hit or miss like it is for a diagnosis of bi polar. You know what I mean? This medicine may work, or it may not work-we will just have to keep trying..... If my nephew could just get some help with the insurance, it would be a load off of my brothers mind.