hi, Tri Sprintec is generic for regular Ortho tri Cyclen not OTC lo, there is no generic for otc lo. Im on Tri sprintec its good for me. I was having some problems with mood swings fatigue, low sex drive, etc. But a few months ago someone on this board told me to try a vitamin B complex cuz the pill depletes B vitamins. It has helped soo much with those side effects. I had a bit of weight gain about 15 pounds but every pill has done this to me and this one is no different I think its just the way my body reacts to the hormones, the brand of pill doesn't matter it has happened with every pill I've tried. I would go off the pill lose the weight go back on gain it back. So you may be different than me, it has made my skin beautiful, and it made me go from a D to a DD, like any pill you just have to try it.