I had a similar problem to yours for several years before I connected it to my thyroid dosage. I was taking synthroid at 112 mcg (a T4 medication similar to levoxyl). Even if I took a lower dosage of synthroid, I would still wake up at about 2 AM and toss and turn the rest of the night; and the next day feel awful because of hypo symtoms from a lower dose of synthroid, and not getting a good night's rest. I started seeing a new endo and he did a full panel of endocrinology blood tests. To make a long story short, my FT3 was very low (below range). He started me on a small dose of cytomel along with the synthroid. After just a few days on the cytomel I started to sleep the whole night through in a deep and restful sleep. That was last November and since then I have settled in to a dosage of 100 mcg of synthroid and 7.5 mcg of cytomel. (the cytomel comes in 5 mcg pills, and I cut one in half for the other 2.5). At that dosage most of the hypo symptoms have been relieved, including lack of energy, and have slept very naturally ever since then. The relief of the sleeplessness has been a great benefit to adding T3 for me.