Spironolactone and hormonal effects

[gradstudent09]

I am a 43 year old woman who has battled hormonal acne most of my adult life. My derm put me on 25 mg of Spironolactone a few months ago. I did not see any improvement, so the dose was increased to 50 mg. Since increasing the amount of the drug, I have noticed my breasts seem more sensitive and am wondering what the hormonal effects of Spironolactone may be. I took myself off oral contraceptives when the HRT controversy erupted and have been suspicious of hormones ever since.

Anyone else with these symptoms?

[morrisun]

I've been taking 100mg of Spiro daily for about 6 months now. I haven't noticed any side effects. Sorry I couldn't offer much help!!

Have you asked your Dr. or Pharmacist about it?

[gradstudent09]

Are you taking it for acne and have you seen any improvement?

[skimom]

Originally Posted by gradstudent09

I am a 43 year old woman who has battled hormonal acne most of my adult life. My derm put me on 25 mg of Spironolactone a few months ago. I did not see any improvement, so the dose was increased to 50 mg. Since increasing the amount of the drug, I have noticed my breasts seem more sensitive and am wondering what the hormonal effects of Spironolactone may be. I took myself off oral contraceptives when the HRT controversy erupted and have been suspicious of hormones ever since.

Anyone else with these symptoms?

I do not think spiro is considered a hormone by itself. It just is a testosterone blocker.

[morrisun]

Originally Posted by gradstudent09

Are you taking it for acne and have you seen any improvement?

Yes, I have PCOS and developed acne (among other things). It cleared up my skin fairly quickly. I could really see an improvement in about a week.