I'm not sure about the tablets. You need to look up the prescribing info on it to see if it is an extended release tablet--it may not be.
If you've been on Prilosec you should taper off as you will get acid rebound (which is why the poster above probably feels bad after 4-5 days off of it).
I use Prilosec in prescription form and it is capsules so I just open them up and empty out about half of the spanules. This is how I taper.
If you swallow a capsule with half how do you swallow the other half? I was not aware that prilosec even came as a caplet. When I had to go off the PPI 's waiting for my H. Pylori test I was told I could use Pepcid or Tagamet and that helped with the rebound. Cheaper, too.