Are you rinsing your mouth after using Advair? You're probably getting Thrush from that - from the oral steroid in it, not from the xopenix. If you have been rinsing, maybe you could ask your doc to switch you to a steroid that comes in a MDI - the canister - and of course a different long acting bronchodialator. That way, you could use a spacer with the steroid, which would reduce your risk of Thrush.