Hi, Plaquenil is also used for various auto-immune diseases, such as lupus, rheumatoid arthritis, etc. I have possible lupus so taht is why I take plaquenil. For malaria, it is used short term. For my problem, it is used long term. I've been taking it now for about 3 years and it helps to keep my flares from being so bad. And it helps with rashes, it even seemed to stop my hair from falling out.
I am not taking any Percocet, though. I dont think a doc would ever prescribe percocet for hives or angioedeam, though. I have not really had angioedema since being Plaquenil, b/c for the most part the plaquenil is controlling my problems. I am pretty sure that my hives & anigo. were related to auto immune disease flares. When I did have it, I always took liquid Benadryl. I dont want to tell you about the dosing i was told to take, as you should discuss that sort of thing with your doctor. Every one is differeent regarding different medications. Any time i've taken any kind of steroid for flares or even for my spine problems, I rarely got hives & never got angioedema. So that makes me think mine is an inflammatory reaction.