This might be a very simplistic approach, but when one is desperate, anything is worth a try. What kind of food do you eat? Is it wholesome, natural, free from chemicals, hyrdrogenated fat, or do you eat fast-food, junk food, lots of sugar, chemicals, processed meals? Do you drink lots of water? Do you take drugs? Do you drink? What I'm getting at is your LIFESTYLE. Could you have some sort of allergy response? (I think I significantly improved my own osteoarthritis condition by altering my diet to avoid meat/sugar/hydrogenated fats/dairy/sodium nitrates/nitrites, etc.) Think about it.