Melinda, 2 of the symptoms my dad had that I believe were considered advanced were abdomonal & ankle swelling, and hemorrage in his esophagus. I had something to do with his portal vein was blocked and the blood flow basically found a new path and blew out vessels in his throat. I believe jaundice is also a later symptom, but he didn't get that for some reason. Incidently, his symptoms were stabilized and he recovered nicely with lots of meds, dieting and, most importantly, he quit drinking.