Iam 44 and have been postmeno. since age 35. I tried the HRT and was so sick, gained wieght, the worst head ackes, mood swing that made people afraid of me, it was awful. I do not tack anything, and I look and feel great. But , I do not have a family history of heart disease, or osteoporosis. I do not smoke, and I have med. bone structure. I lift wieghts, very heavy weights, exercise, have a good diet, and stress free life style. These are all things that need to be taken into concideration when deciding on treatment. Do you have breast cancer in your family? I do not, so I could take the HRP and not worry about added risk from long term use. I hope this was helpful. Oh and I look great! Loke I am 35.