You didn't say how many times per day your dad is taking the Sinemet 25/100.
I conducted a survey elsewhere on what pd drugs pwps were taking and how long they had been diagnosed with pd. Their was every combination that i could think of, but out of sixteen pwps, everyone was taking Sinemet 25/100. One person was taking the drug 12-14 times per day. Three to four times a day was about average. Most of the pwps were taking a combination of drugs.
Kimi, did you say your dad had just started on pd medication?
The problem might be it hasn't been long enough for the Sinemet to relieve his symptoms or he might need an adjustment of his Sinemet.
It's always best to keep the Sinemet dose as low as possible, because eventually he will develop dyskinesia
if the dose is increased to much.
As the survey showed everyone's dose is different.
Have a good one. Bruce