I got a big smile when I saw this board. I'd like to share my (luckily) small experience with RLS. Flying back home for xmas 2000, I was taking a red eye for the first time, so I took a tylenol pm. I had never taken one before, and wasn't in any pain, but obviously wanted the sedative quality of it. I soon became sorry I took it so early in the flight. I developed MAJOR RLS, and in coach that ain't no fun. I then basically had this for the next 3 months or so, and my doctor didn't know what to tell me. What made it worse was for my job at the time, I primarily sat a desk or drove most of the day. Let me tell you, I was running 10 miles a day under that desk. As you all know, at night it was even worse trying to get to sleep. But, like I said, luckily it eventually stopped. I remember I had wisdom teeth surgery the end of march that year, and it was gone by then. All in all, it's hard to imagine that one tylenol pm did this to me, but its the only thing i had before it started...