I'm new here, just waiting for salivary gland biopsy to confirm the SS diagnosis, but I am positive I have it -- my Shirmer's test was 0 after 5 minutes - "dry as a bone" were the exact words she used about my eyes! Yikes!
Just want to share that my rheumie started me on Plaquenil about a month ago, and already my fatigue has improved a lot! By a lot, I mean going from barely getting out of bed and only able to shower every 4 or 5 days, to being up every day and only needing a rest now and then during the day. This week I took a shower 2 days in a row and even started a little house cleaning! This was a huge change for me! While there is a very SMALL risk of vision loss with Plaquenil (that is why you need regular eye checks with an opthamologist), it is extremely rare. So I would hate anyone with SS to avoid trying Plaquenil just for that one reason, especially since there are many professional research articles online that say it can be quite helpful for both lupus and SS. Having such dry eyes makes me want to get my eyes checked anyway, so I don't see it as a burden at all, especially with the great response I'm getting.
I hope others will share their experience with Plaquenil too.