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Sjögren's Syndrome Message Board
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Old 04-18-2009, 08:16 PM   #1
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surreygal HB User
ss and heart problems?

Hi there:
I read an interesting post from last year that unfortunately is closed, so I'll throw out this question and hope for feedback on it.
Does anyone know of a correlation between heart problems and Sjogren's? The reason I ask is that I was born with a ventricular septal defect, which is a fancy way of saying a great big hole between the lower 2 chambers of my heart. These defects sometimes spontaneously heal, but after multiple trips to the ER with a very blue baby, I think my parents convinced the doctors that I could benefit from medical intervention if I wished to reach toddler-hood. At 4 1/2 years of age I underwent open heart surgery, a very maverick procedure in 1967, done by a specially trained team from the Mayo clinic, no less! (Don't I feel special!) Despite being told I had a 75 % chance of dying from the operation, I pulled through strong and stubborn. In fact, my heart is in phenomenal shape, and should stop ticking when about 110 years old, my cardiologist tells me. I am an avid cyclist and I also love hiking/walking and generally keeping fit, so I guess this has helped my cardiovascular health.
The reason I ask about the SS link is because my mother nearly died of Grave's Disease when she was in her mid thirties. I am well aware of the close association between that thyroid disease and Sjogren's as they are both caused by the same rogue anti-body. I am wondering if the heart disease I was born with may have been a foreshadowing of further trouble to come for me. I realize that auto-immune disease is thought to have a mitochondrial association, and this is passed down only via the mother's genetics. I wonder if this whole mess is actually my mother's fault! Any thoughts from anyone about this? Just curious...

 
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Old 05-13-2009, 07:14 PM   #2
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thus HB User
Re: ss and heart problems?

What is the mitochondrial association? Is that a reference to maternal DNA?

 
Old 05-15-2009, 10:22 AM   #3
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surreygal HB User
Re: ss and heart problems?

Quote:
Originally Posted by thus View Post
What is the mitochondrial association? Is that a reference to maternal DNA?
Hi there:
Mitochondrial DNA is material (genetic) inside a cell--so very small material. There are different types of DNA. Mitochondria is known as "the power house of the cell" and is only transmitted to off-spring from the mother.
Cheers! Surreygal

 
Old 05-16-2009, 12:00 AM   #4
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Re: ss and heart problems?

Thanks for enlightening us on a subject that should be delved into. It is a fascinating and complex subject that will take me years to master.

 
Old 08-22-2009, 09:59 AM   #5
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Re: ss and heart problems?

Quote:
Originally Posted by surreygal View Post
Hi there:
I read an interesting post from last year that unfortunately is closed, so I'll throw out this question and hope for feedback on it.
Does anyone know of a correlation between heart problems and Sjogren's? The reason I ask is that I was born with a ventricular septal defect, which is a fancy way of saying a great big hole between the lower 2 chambers of my heart. These defects sometimes spontaneously heal, but after multiple trips to the ER with a very blue baby, I think my parents convinced the doctors that I could benefit from medical intervention if I wished to reach toddler-hood. At 4 1/2 years of age I underwent open heart surgery, a very maverick procedure in 1967, done by a specially trained team from the Mayo clinic, no less! (Don't I feel special!) Despite being told I had a 75 % chance of dying from the operation, I pulled through strong and stubborn. In fact, my heart is in phenomenal shape, and should stop ticking when about 110 years old, my cardiologist tells me. I am an avid cyclist and I also love hiking/walking and generally keeping fit, so I guess this has helped my cardiovascular health.
The reason I ask about the SS link is because my mother nearly died of Grave's Disease when she was in her mid thirties. I am well aware of the close association between that thyroid disease and Sjogren's as they are both caused by the same rogue anti-body. I am wondering if the heart disease I was born with may have been a foreshadowing of further trouble to come for me. I realize that auto-immune disease is thought to have a mitochondrial association, and this is passed down only via the mother's genetics. I wonder if this whole mess is actually my mother's fault! Any thoughts from anyone about this? Just curious...

 
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