Re: Need HELP for a friend. Suspect Sjogren's
Yes, it sounds as though she might have SS. I have chronic throat flem, too. The "gold standard" for SS is a lip biospy, as those tests seem to be the most definitive. They too can give false negative results, but they are more reliable than blood tests. I'd recommend the procedure be done by an Oral Medicine Specialist, or a dentist who is very familiar with SS. Also, ensure the pathology is determined (the spec is read) by a pathologist who is very familiar with SS. The blood tests that may show results are: ANA,ENA,SS antibodies and Sed Rate (ESR). C3,C4 counts are usually low and Serum Protein Electrophoresis tests can be useful, too.
Schirmer testing is less reliable, which involves testing how much fluid is produced by the eyes. (The "sicca" symptoms may not develop until the SS is well established--mine didn't develop until very recently. Sicca symptoms are dry eyes and mouth.) I had neurological symptoms mimicking multiple sclerosis, including brain lesions, and I didn't have typical SS symptoms until a few years ago. I also have vasculitis (inflammation of blood vessels) that causes redness and rashes, as well as small purple spots and bruises (in places where no injury has occurred).
Good luck with your friend. I hope she gets the answers she needs. Take care.