I have been struggling with thyroid disease for 30+ years - first they had to kill mythyroid and ever since that time I have been a yo/yo with too much synthroid or not enough. It is frustrating. Also I have been diagnosed with Sjogrens and Fibromylagia. The constant aching and the fatigue is sometimes more than a persona can handle. I work full-time, have a sick mother that I am a care giver to and with all this I'm totally exhausted. I have been on placquinel for 5 months - didn't do a thing. I tried lyrica last summer, it helped so i just started taking it again but have noticed that my feet and hands are swollen. I also have restless leg at night and between the pain the the movement of the leg I really hate to go to sleep, but am exhausted. I also went off of requip since it was not doing anything but making the restless leg worse. I'm ready to get off all my meds and start over. I have high blood pressure, high cholesterial, IBS, Acid Reflex, and I just feel like a total mess. Is there anything out there that can stop the aching and the discomfort.