I am on an oral antifungal, sporanox (itraconazole) , and was told nothing from my Dr or pharmacist about drinking or taking tylenol. I was told in quite detail that its important to take the pill with something acidic (coca cola or orange juice) and no less than 1 hour before you eat. When you do eat, it should contain fats to help the medication get into your blood stream.
To be sure, I double checked with a drug interactions guide, and although the increased risk of liver damage was mentioned, along with other medication interactions, there were no other warnings.
I dont think my doc nor pharamiscist would put me at risk by neglecting to tell me something imporant.. Maybe itraconazole I'm taking is different from the two drugs you just mentioned, and if so .. you might want to start out with sporanox if only for the compatibility with drinking/tylenol.
Also, I've been on it BID for 5 days .. I dont feel any side effects at all.
But, its also not noticeably working to cure my ringworm either, LOL. But nothing seems to... everything just seems to "Get it angrier"