I am also taking Zoloft...but also contemplating changing to Remeron. This is my OPINION only, but from what I read, Remeron is a far superior medication, and may have more robust effects in treating anxiety.
I have sourced a few research articles on the efficacy of Remeron (from PubMed) in treating GAD; so far, very encouraging results. One study said that Remeron could be more effective in treating GAD than depression. It is likely to be indicated for both depression and anxiety in the near future.
Let us know if you decide to change, and how it works for you! <IMG SRC="http://www.healthboards.com/ubb/smile.gif">
I have been using remeron for almost a year now, 30mg a day at night. It has definetly helped with depression and controlling anger. But i dont notice it helping for anxiety or OCD, and i haven't found anything that has helped that. It may help for you though,im just telling you my experience with it. Also i have tried prozac and paxil neither of them helped me any, paxil i went as high as 80mg. I have not used a med yet that has helped me with anxiety or OCD,I think my case is more sereve than other people. So the remeron may help for you, hopefully more users will give feedback.
From what my doctor told me, Zoloft is an "activator", Paxil and Prozac are more sedative type. Celexa is in the middle.
Remeron has sedative effects, but they go away with time.
I started on Zoloft and had to stop after my third dose. The side effects were too much. I was on 50 mg/day.
After reading about Remeron I asked my doctor and he got me free samples.
The main reasons I was attracted to Remeron where the side effects (sleepiness and weight gain). All my depressions cause me insomnia (one of the side effects of Zoloft). The lack of sleep makes my depression stronger, so I need to sleep in order to fight the depression. Also, during my last depression, I lost about 16 lbs (from 178 to 162). I am 6 feet tall. So, with Remeron I am helping myself sleep and gain weight.
Now, another reason for me wanting Remeron: no sexual side effects. So far so good!
I do not know how long my doctor will keep me on it (I suffer from SAD and reactive depression). I do not want to become dependant on it, but I do not want to go back to who I was before it.
Here's a couple of abstracts from PubMed on Remeron (mirtazapine) and use for anxiety:
Mirtazapine in major depression with comorbid generalized anxiety disorder.
J Clin Psychiatry 1999 Jul;60(7):446-8
BACKGROUND: A high proportion of patients with generalized anxiety disorder (GAD) have comorbid depressive illness. The presence of anxiety in depression has significant prognostic implications. Because of mirtazapine's early anxiolytic effects, the present study was undertaken as a preliminary investigation in patients with a diagnosis of major depression with comorbid GAD. METHOD: Mirtazapine was administered to 10 patients with DSM-IV major depressive disorder and comorbid GAD in an 8-week open-label study. Mirtazapine was increased from an initial daily dose of 15 mg to a maximum daily dose of 45 mg. RESULTS: Patients were found to have significant reductions in Hamilton Rating Scale for Depression scores, Hamilton Rating Scale for Anxiety scores, and Beck Depression Inventory scores, with improvement noted after the first week of therapy and continuing improvement over the 8 weeks of study. CONCLUSION: These positive preliminary findings support the further investigation of mirtazapine's potential value as a treatment for generalized anxiety disorder in addition to its established efficacy as an antidepressant drug.
Mirtazapine: other indications.
J Clin Psychiatry 1999;60 Suppl 17:36-40; discussion 46-8
During the last decade, it became evident that antidepressants may represent a useful treatment option for a variety of primary psychiatric disorders other than depression. Improved understanding of both underlying etiology of these disorders and pharmacologic modes of action of available treatments has led to an improvement in conditions such as panic disorder, generalized anxiety disorder, obsessive-compulsive disorder, posttraumatic stress disorder, and premenstrual dysphoric disorder. In addition, evidence is accumulating that some new antidepressants may be of therapeutic value in treatment of some subtypes of depressive disorder previously unresponsive to treatment or difficult to treat, such as seasonal affective disorder, depression with atypical features, and recurrent brief depression. Mirtazapine is an antidepressant with mode of action different from other currently available antidepressants. A review of currently available data of mirtazapine's use in indications other than depression and in some types of depressive disorder is presented.