Hi Debbi. I can't believe your doctor won't be seeing you for a month! He or she should at least have a phone conference with you to explain your results and the treatment options (as necessary).
We're not doctors, but some folks here are trained in science or medical fields. And we know where to look to find answers. Let's see if I can translate some of this gobbledygook. I've gleaned this information from a variety of medical websites so, unfortunately, it's still pretty technical. Hopefully, I've interpreted them properly. (Scroll down to the very bottom for suggestions of what to ask your doctor):
Epithelium or Epithelial Cells
Impression: Abundant follicular epithelium with microfollicle formation in a background of abundant colloid and hemosiderin-laden macrophages (see comment) |
Comment: The specimen consists of follicular epithelium composed of cells with relatively small nuclei. Numerous microfollicles present. These features are most suggestive of a follicular lesion (hyperplastic vs. neoplastic) possibly in a background of nuclear goiter.
- Epithelium is the type of glandular tissue that is sampled in an FNA Biopsy. Follicular Epithelium
- Follicles are the type of cells (with nuclei) that compose the thyroid gland. "Normal" thyroid tissue would have follicles that are evenly dispersed; An FNA of normal tissue would reveal low columnar follicular cells surrounding pink colloid (containing thyroglobulin produced by follicular cells). Colloid
- Colloid is a a gelatinous or mucinous substance found in tissues that naturally surrounds the follicular epithelial cells. In a normal thyroid gland, colloid should predominate with clusters or sheets of follicular cells with wispy cytoplasm (cellular fluid) and indistinct cell borders. Abnormal FNA results may identify nodules or cysts filled with colloid. Thyroglobulin
- an iodine-containing protein of the thyroid gland that is the precursor of thyroxine (T4 hormone) and triiodothyronine (T3 hormone). The body uses Thyroglobulin to produce thyroid hormone. Nuclei Size
– Follicular Cells typically have large nuclei. Cells with small nuclei may suggest an abnormal degeneration in the cells. Hemosiderin
- a yellowish brown granular pigment that is formed in some phagocytic cells by the breakdown of hemoglobin and is probably essentially a denatured form of ferritin (a form of iron found in the blood). Phagocyte or Phagocytic Cells
– see “Macrophage.” Macrophages
- a cell (typically a white blood cell) that engulfs and consumes foreign material (as microorganisms) and debris. Phagocytes are macrophages. Neoplasm or Neoplastic
- a new growth of tissue serving no physiological function (such as a nodule) Macrofollicle
– a type of clustered follicular cells. Colloid nodules contain macrofollicles. Microfollicle
- a type of clustered follicular cells. Hurthle cells contain microfollicles. Hyperplasia, Hyperplasm, Hyperplastic
- an abnormal or unusual increase in the cells composing a tissue.
I found a really technical website that described something similar to the impression you posted: Various Types of Euthyroid (healthy thyroid) non-neoplastic conditions
1. Indications of a Hematoma/Hemorrhage into the Thyroid
- The sampled fluid includes Brownish fluid "chocolate" (old blood) that disappears with aspiration but may reaccumulate over time. FNA shows Red cells predominate with numerous macrophages. Results may show ingested debris and/or hemosiderin should lack ciliated or columnar epithelium; may have sparse degenerative follicular cells.
This is the closest thing I found to your FNA diagnosis. I'm not certain, but it sounds as if you may have a nodule with some hemorrhage. Your results did not mention "capsule infiltration" (an indication of malignancy), so I'm glad for that. But I think your results suggest follicular and Hurthle cell abnormalities.
Is it possible to call your doctor and ask him/her to explain these results in layperson's terms? You may also want to ask for follow-up tests, such as an Iodine Uptake Scan to determine if your nodule is hot (producing more thyroid hormone than normal), warm (producing the same amount of thyroid hormone as normal thyroid tissue), or cold (not producing thyroid hormone). Cold nodules require a closer watch.
[This message has been edited by ArtfulD (edited 11-16-2002).]