Thanks for the information. For the last 2 weeks, I have been getting up 1 hour early to take my meds. I got into trouble by eating too much soy, and taking the Armour with all my other vitamins supplements. I am feeling so much better now because my muscle cramps and pain have gone!! Also I am less tired and I am told, I am much more charming, again. So I guess it is worth the effort to get up and take the meds.