Originally Posted by rlboone
Wow, you sure know your stuff.
Let me see if I understand what you told me. Because of the presence of the TPO antibodies and I am hypothyroid the chances of me have Hashimoto's is greater. Or do I missunderstand and my TPO level has to be above 50 to be diagnosed with Hashimoto's.
The presence of TPO antibodies and/or Thyroglobulin antibodies is often used to make an educated guess as to whether a person has Hashimoto's or not, but, the only way to truly diagnose Hashimoto's is to do a biopsy of thyroid tissue.
So, you are right that the presence of TPO antibodies means you very well might have Hashimoto's, but even a count of 1500 would not tell you that you definitely have Hashi's.
The two antibodies that are associated with Hashis are different in their actions:
Thyroid PerOxydase or TPO antibodies attack the mechanism in your thyroid gland that actually produces thyroid hormones. While these are elevated, your will likely be hypo, then once the level goes down, you will have less ability to make thyroid hormones and your thyroid gland may grow larger to accomodate, or you may just simply stay hypo. Either way, treatment is advised.
Thyroglobulin antibodies attack a protein in your thyroid gland an in your blood that is used to store thyroid hormones for later use. While this antibody is active, it causes a rise in throid hormone levels in your blood, and you may go hyper. This causes free levels of thyroid hormone to be elevated, while your Total thyroid levels will be the same. This is why many smart doctors rely on the Free T3 and Free T4 tests rather than the Total T3 and Total T4 tests.
You can see how patients with antibodies might have thyroid levesl that fluctuate--sometimes quickly--and need close monitoring if the antibodies are active.
Not that I truely understand the difference between suffering from a thyroid cond like hypo or having been labeled having an autoimmune disease. If I'm not mistaken the treatment is the same or not?
The treatment is the same regardless of why you are hypo. However, if you are Hyper, due to antibodies attacking, then treatment may vary, depending on what antibody is attacking.