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Old 12-02-2004, 12:17 PM   #1
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Question Meep or Midwest, have a little question?

I have heard that if you have had hypoT for a long time the TSH can be suppressed. Can you tell me if that is true?
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Old 12-02-2004, 01:08 PM   #2
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Re: Meep or Midwest, have a little question?

Quote:
Originally Posted by Lady50
I have heard that if you have had hypoT for a long time the TSH can be suppressed. Can you tell me if that is true?
I believe it to be true. My TSH at diagnosis was 2.6, but my Free T3 and Fere T4 were low in their respective scales. It seems that after long-term hypothyroidism without treatment, the body gets used to a lower level of hormoen and the hypothalamus and pituitary decide that this is an OK arrangement.

I dont' have proof, other than ancecdotal stories, but that's enough to convince me. Dr. Dommisse mentions something similar in his Optimal Treatment paper:

Quote:
Normally, the anterior pituitary will secrete enough TSH to maintain adequate thyroid hormone levels. When this fails to occur, either grade-1-primary or secondary hypothyroidism is considered to be present. There seem to be subtle, conventionally called 'subclinical', failures of the anterior pituitary to produce sufficient TSH in response to low thyroid hormone levels that cannot be explained solely by the traditional form of secondary hypothyroidism (secondary to a pituitary tumor or outright pituitary failure, as in Sheehan's Syndrome: postpartum hemorrhage or infarction of the pituitary gland). This could also be due to a tertiary hypothyroidism (where the thyrotropin-releasing hormone ~ TRH ~ from the hypothalamus fails, for poorly-understood reasons, to stimulate the anterior pituitary to secrete adequate amounts of TSH), or to a TSH_specific hidden hypopituitarism.
I believe that long-term untreated hypo can be one of the causes of this. It is my belief that Hypothyroidism slows EVERYTHING down eventually--including the Hypothalamus and the Pituitary.
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Old 12-02-2004, 01:29 PM   #3
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Re: Meep or Midwest, have a little question?

Thanks Danny, As you said it can slow everything down and I believe it. I was on PTU for two years and kept hypoT most of the time(because of miscommunication between the doctor and I). Had RAI and kept hypo for 4 months. That could be my problem.

Thanks again for very good info.
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Old 12-02-2004, 01:32 PM   #4
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Re: Meep or Midwest, have a little question?

Quote:
Originally Posted by Lady50
Thanks Danny, As you said it can slow everything down and I believe it. I was on PTU for two years and kept hypoT most of the time(because of miscommunication between the doctor and I). Had RAI and kept hypo for 4 months. That could be my problem.

Thanks again for very good info.
I'm starting to wonder if a lot of people with Graves disease are misdiagnosed because of TSH alone?! You said you were hypo to begin with and then when you started on meds, I guess they decided you had Graves disease? It doesn't make sense.

 
Old 12-02-2004, 01:39 PM   #5
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Re: Meep or Midwest, have a little question?

I must have brain fog I had graves and was put on PTU but my doctor did not tell me all that time that I am suppose to reduce the dose when the thyroid hormones are at normal ranges. Of course he always said the test were okay. At that time I did not know that you don't just go by the bloodtests. You go by how you feel. My doctor was not very knowledgable about graves disease.

I actually thought it was menopause symptoms.
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