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Old 03-11-2005, 11:51 PM   #1
Join Date: Mar 2005
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Unhappy What does Elevated Thyroglobulin Mean? Do I have Cancer? I'm so afraid. Please Hel

I have had a long journey with being hypo for many years now. As I see most of you already know here, like you all I have either been misdiagnosed or under-treated for over 12 years. I will tell my long story in a later post.
** Finally a little over a week ago I had my M.D. refer me to an Endo because I truly feel like I am going to die if I do not get the correct treatment. I am 42 years old with a 6 year old daughter to worry about & I am scared. I received a letter in the mail saying:.....

**1. Your thyroid levels were low...yet my M.D. was telling me they were normal!!
** 2. You have positive thyroid antibodies indicating you have an autoimmune disease causing your underactive Thyroid...
** 3. Your THYROGLOBULIN levels were elevated at this visit.
** 4. Your Thyroid Ultrasound showed irregularity, but there was no distinct nodule which was larger than 2 to 3 mm in size.
My M.D. had me on 0.025 of Synthroid & the Endo has upped my Synthroid to 50 mcg & wants to see me in 2 months.
I have never even heard of THYROGLOBULIN (evean after 12 years of this) but have searched a little on the net & it seems it can indicate cancer.
Now I am very scared. Should I wait 2 months as the Endo says & be checked again or should I insist on being checked sooner?
I would greatly appreciate your thoughts on the meaning of this letter. Thanks in advance.
What a wonderful website. I wish I had found it years ago. May all you wonderful people be blessed for all the help & support you give here.

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Old 03-12-2005, 09:03 AM   #2
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Re: What does Elevated Thyroglobulin Mean? Do I have Cancer? I'm so afraid. Please Hel

Doctors! Couldn't you just scream?
...there was no distinct nodule which was larger than 2 to 3 mm in size
If this is true, it's highly unlikely you have thyroid cancer. Nodules aren't even biopsied until they reach 1 cm because the risk of anything smaller is minimal.

I did a brief search on elevated Tg. If you search by excluding the words "carcinoma" and "cancer", you'll find references to elevated Tg sometimes caused by iodine deficiency. That isn't to say it explains your case, but it does confirm that there are other causes besides cancer.

Thank goodness someone had the sense to raise your dose. The .025 you were taking isn't enough to keep a flea going. My former endo told me it's considered a "non-dose", and that she never prescribes that little for anyone.

The two-month waiting period after a dose increase is pretty common. It takes that long to determine what the increase in T4 is doing to your blood levels. You can, IMO, safely wait that long.

Old 03-12-2005, 09:15 AM   #3
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Re: What does Elevated Thyroglobulin Mean? Do I have Cancer? I'm so afraid. Please Hel

Don't worry too much about the lack of help. You'll have to do some research on your own most likely. It sounds to me you have Hashimoto's Thyroiditis - not cancer, so relax....I know its scary to think about the C word but its pretty rare.

If it helps, I have Hashi's and my Thyroglobulin (Tg) and Thyroid Peroxidase (TPo) Antibodies are through the roof - it is very common in people with Hashi's and probably 80% of the people on these boards test positive for that.

As for your "irregular" thyroid....again...relax....the antibodies you have attacking youir thyroid are causing it to swell a little and become more grainy than normal....this again is an indication of Hashi's in most cases.

Cancer is usually found on the thyroid with either a very rapidly gorwing tumor, which you do not have or a slow growing, very firm mass that feels like a marble. Of course, there are other situations where cancer can be prevalent, but from what you described, it does not sound like cancer to me, but Im not a doctor. I have, however, been through the wringer with my Hashi's and am fairly educated on the subject through lots of research over the last 2 years of being misdiagnosed.

Last edited by nastyhashi; 03-12-2005 at 09:17 AM.

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