I had a total thyroidectomy 3-8-05. Initially, I felt so good, like I was Queen of the World and suddenly everything just crashed. I thought I needed more medicine--anything besides a "mood altering" drug or anti-depressants. I was so sure I needed some t3 and even vented on the board after seeing my PCP. Well, to be honest, after reading the replies and watching Brooke Shields on Oprah, it dawned on me, I need help. You know, what? YES I am depressed my TT did not cure it all. I'm on .125 of synthroid but I need something else. I am not myself. My house is a total mess, my patience is shot and my coworkers are suffering. I don't think it's fair to anyone to have to put up with me in the state that I'm in. I had the opportunity to meet with a new doctor and I told him..shame or no shame...I need some medicine for this depression/panic and however long it takes for me to get myself together, I am willing to take it. He prescribed Zoloft me and hopefully I'll notice a change soon. Anatomically, I am glad the thyroid isn't choking me anymore but mentally, I am in the pits. I'm not trying to discourage you but just like someone posted to my reply, if you need something to get you through, by all means, get it.