If your thyroid levels are in the right place in your lab ranges, your goiter should shrink. When my Ft3 and Ft4 are in the upper part of the range, my goiter disappears and I don't feel like there is a lump in my throat when I swallow.
I was doing great until I decided to use this estrogen patch, without raising my Armour dose. That was a big mistake, because I went hypo again, because you need more thyroid replacement while taking estrogen. My estrogen patches are now in the trash. I should know better.
When I am not hypo, my thyroid is not swollen, but when I was hyper, my thyroid was swollen too. So, any irritation to the thyroid, will make it swell.
Your goiter will not shrink until your Ft3 and Ft4 are in the ranges where you feel your best.
I am a little bit hypo right now and it makes my arthritis feel worse in my shoulder, more nasal stuffiness,little depressed, there is a feeling of a lump in my throat. My bottom front teeth ususally have a little pain in them.
It does take time for the goiter to shrink. I went hypo 5 months after the RAI while taking an antithyroid drug.
Betty
throat pain and enlarged thyroid post Radioactive Iodine 
