Hi mangojunky, welcome to the board
I don't take any supplements, sorry - no experience there.
As far as the thyroid meds take 2 hrs after eating or 1 hour before with a glass of water. I find am is best and drink my coffee right after if it is ready - a lot of others here do this also and I guess have not noticed any problems with it. Calcium does interfere with the thyroid med absorption, so I don't eat any dairy products or take any "One a day" type vitamins with calcium until 4 hrs after the meds.