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Old 10-21-2006, 11:18 AM   #1
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sudufu HB User
Exclamation does HYPO = cranky, lack of sleep & anxiety???

some background: one Thy lobe removed 1 yr ago. I'm on my 3rd Doc (1 of Osteopathic medicine this time) in my 9 month meds RolLerCoaSteR. I've taken Synthroid (yuck), Armour (think it could of worked but Dr #2 didn't want to tinker with it) & have been on Cytomel since May. Now on Cyt / Levoxyl combo. I'm 47, always been a chunky monkey, yet in good health excluding this. I've been ON/off anti-d meds for some years, until the wonder drug Cytomel.

Someone tell me this gets BETTER!!?!!!?? 1-2 weeks ago I was in a manic cranky & high anxiety phase , , , 5+ weeks prior we'd added .025 mcg's of Levoxyl to my exsisting 50 mcg's of Cytomel. My T4's are SERIOUSLY low, .4, due to Dr #2's incompetence. Don't think that tiny increase will do much, but we have to take it one step at a time.

I have times of HIGH anxiety, lack of patience (teach elementry kids) & depression, all while exsisting on 4-5 hours of sleep (if I don't take some sort of sleep aid). My question is this: When my Thy hormones are closer to NORMAL (geeeeeeezZe how I hate that term) will the irratation, trouble sleeping & anxiety GO bye, B-Y-E ? ?

I did labs Friday & see the Doc next week. I'm going to ask to increase my Cytomel as T3's are only a few points IN range & think that will help with my anxiety & irritation, maybe sleep too. Also think I should ask for a sleep aid because LACK of it will make a person IRRITATED

Thoughts? Suggestions? What did *YOU* do to help get yourself through the Thy med leveling process???

Thanks
Sue

p.s. my last labs (O-L-D ) went like this:
T3 u/t = 25 (22-35)
T4 total = 1.5 *L* (4.5 - 12.5)
free T4 = .4 *L* (1.4-3.8)
tsh = 1.75 (.40-5.5)
Did want anyone thinking I was OVER medicated <<~now THERE is a joke !!

 
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Old 10-21-2006, 12:23 PM   #2
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Red Maple HB UserRed Maple HB User
Re: does HYPO = cranky, lack of sleep & anxiety???

Sue, it seems that there is definately some tweaking of your thyroid meds a bit to a more comfortable range. However, not to discount the thyroid stuff, but I am 53, menopausal, and for me the cranky, lack of sleep, and super anxiety was a result of meno. rather than thyroid. My doctor got me a mild antidepressant for the crankiness which evened out my moods, some ambien for insomnia, as needed; and ativan for the anxiety, also as needed. It worked wonders for me. I would usually fall asleep ok, but would wake up around 1-2 AM and not be able to go back to sleep unitl about 5 AM, then I had to be up at 6 for work. Like you I was running on only a few hours of sleep a night. I am also on Climara-Pro a very mild bio-identical HRT patch. By adding those meds. I was finally able to get some much needed rest. I hardly take the ambien or the ativan anymore, it was really a temporary thing to get me back on track.

I don't know if your situation is the same as mine, but since you are 47 you likely are in peri-menopause, with your fluxuating female homones also comming in to play with your health. I thought I would mention my experiences. Good Luck to you, and sorry if I'm barking up a wrong tree by suggesting it could be meno...

 
Old 10-21-2006, 02:25 PM   #3
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sudufu HB User
Talking Re: does HYPO = cranky, lack of sleep & anxiety???

thanks Red Maple ~
June 06 when my last full panel of bloodwork was run, my hormones were fine. B-U-T, waking up at 1-2 am sounds AWFUL familiar. My 1st Doc forgot I'd had lobe removed & put me on prempro b/c of my headsweat. I took pp until a month after starting Cytomel. I spotted for a month b4 quitting PP, because those medicines just don't mix. Maybe I should ask for another meno medicine because another friend mentioned female hormones & NOT SLEEPING.

Yet, the SERIOUS cranky, lack of patience & irritation didn't start until we added levoxyl to the Cytomel. When I took only Synthroid at the onset of my thy-med treatment, I felt like I was taking depressants. And what i'm feeling now could be the pre-curser to that.

ANY info is greatly apprecited
Sue

 
Old 10-21-2006, 02:37 PM   #4
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Re: does HYPO = cranky, lack of sleep & anxiety???

I too am curious about anxiety, depression, low pain tolerance,etc going along with hypothyroid???
I am not on med yet, as my alternative doc says I am hypothyroid, my
family doc says I am not that my levels are all within nl range ( I know we
all heard this before and many of you have been there). I see the alternative
next week and will probably go his direction with trt. My levels do appear
to be wnl except for my antibodies which my family doc says could have
come from 36 yrs ago when I had my daughter and had post-partum
hypothyroidism.
Levels:
FT4- 1.1 (range .8-1.8)
F53- 302 (range 230-420)
TSH- 3.56 (range .40-5.50)
Thyroid Peroxidase Antibodies 362 (range less than 35)

Alternative suggested low dose Levothyroxine. Family doc feels this will
throw me into hyper.
Appreciate hearing from anyone who has been in this situation.

Also Redmaple, what anti-dep did your doc give you??

Thanks all.
Jodianne

 
Old 10-21-2006, 02:53 PM   #5
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Re: does HYPO = cranky, lack of sleep & anxiety???

FT4- 1.1 (range .8-1.8)
F53- 302 (range 230-420)
TSH- 3.56 (range .40-5.50)


jodianne ~ To me your T4's are just in range. My understanding is that we feel better in the upper 1/3 of that range. By my squirelly math, that is 1.45+ on up. And your TSH *is* high as most people feel optimal between 1-2. I don't know what your symtoms are, but I'd tend to listen to alternative who wants to treat your symtoms, rather family doc who says you're NORMAL (yes - NORMAL does drive me NUTS as my old primecare-Dr said I was just that w/ TSH of 4.85 which is 3 times *my* normal - but she didn't bother to look at labs from 5 months prior to realize that)

Last edited by sudufu; 10-21-2006 at 03:00 PM.

 
Old 10-21-2006, 06:31 PM   #6
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Re: does HYPO = cranky, lack of sleep & anxiety???

Sudufu,
Thanks for replying. At one point my tsh was 5.12, family doc just told me
that my levels were nl at that time. She chked in 1 yr and tsh was 230 so
her theory is until it is close to 5.5 or over and stays, don't treat. Now I
know from reading of others on this board that that is nuts!! I actually
started feeling lousy in 2003, anxiety, poor digestion for which I went through
all kinds of tests and nothing could be found, depression which I never had
in my life before. Now in the last yr, I still have anxiety, depression, dry skin,
brittle hair, tired by 2 to 3 pm. I'm constantly straining muscles in my back
and neck and arms. According to a lot on the boards these are symptoms
of hypo. Although I thought anxiety went with the hypers. My family doc
says if I take the Levo, I'll have more symptoms of anxiety etc, and that is
what scares me.
Again thanks for replying, I've learned so much from everyone on these
boards, really nice the way everyone tries to help the other!
Jodianne

 
Old 10-22-2006, 01:42 PM   #7
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Red Maple HB UserRed Maple HB User
Re: does HYPO = cranky, lack of sleep & anxiety???

Jodianne, not knowing your family doctor and not wanting to be disrespectful to him...but the most current information from the Board of Clinical Endocrinologists is a range for TSH of 0.3 - 3.00 as normal. Most savvy doctors will treat hypo symptoms with a trial dose of hormone replacement meds. when the TSH gets to 2.5 Your family doctor probably isn't a specialist in thyroid treatment and is unaware of the most current standards for Endocrinology. That doesn't mean he is a bad doctor, just that thyroid treatment isn't his primary speciality. With the symptoms you describe and the labs you posted, I would guess you have mild Hashimoto's syndrome. It's the most common cause for hypothyroidism in the US. Your FT's are low on the range and TSH is too high IMO. I feel best when my TSH is around "1" and my FT's are in mid-range rather than the upper third; but that's just me, most here are the board feel best with FT's in upper third of range.

I really doubt that a small dose of levo. will cause more hyper symptoms. The anxiety could be from another cause, like worrying about your health since you have so many miserable symptoms! If you do become more anxious, it's easy to remedy by just stopping your meds for a few days and see how you feel. You also may want to try an anti-anxiety for a short time like Ativan (I like that one) or Xanax to see how you respond to that. As I said in my post to Sudufu, for me the anti-anxiety is as needed only, and proved to be something I only needed temporarily to get back on track.

Try to convince your doctor to allow you at least a small dose of trial thyroid replacement hormone medication. If he still refuses, then I'd try to find someone else who is more thyoid savvy.

Best of Luck!!

Last edited by Red Maple; 10-22-2006 at 01:45 PM.

 
Old 10-22-2006, 05:29 PM   #8
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sudufu HB User
Re: does HYPO = cranky, lack of sleep & anxiety???

I say the upper 1/3 of the range also, but in my 9 months of Thy meds RolLeRCoaSter, just being a few points IN is all I've made. (now my T4's are SERIOUSLY in the toilet) Maybe just above 1/2 way mark will be the cats meow for me also.

I forget what kinda NORMAL feels like

 
Old 10-23-2006, 11:49 AM   #9
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jodianne HB User
Re: does HYPO = cranky, lack of sleep & anxiety???

Sudufu,
I posted a reply with symptoms before but it didn't seem to show up. I've
had slow digestive problems the last two yrs, sensitive to cold, anxiety
and depression, tired by 2 to 3 pm, low pain tolerance, mentally just not
able to handle things like I did before. My main concern is the anxiety and
depression. Did you or do you know of anyone else who had anxiety and
depression and after taking med this resolved??? My family doc thinks if
I take Levo while my levels are in nl range (by her standards) will push me
to hyper and I will have more anxiety.
I appreciate your reply and hope to hear from you again and anyone else
who could shed some light on this.
Jodianne

 
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