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Thyroid Disorders Message Board
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Old 04-21-2008, 02:20 PM   #1
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Can low Ferritin (or something else) block T3 binding and increase circulating FT3?

Something is causing my FT3 to be +50% (of range) higher than my FT4, but still "Normal".

(TSH is at about 15% of range, FT4 is about +10% from TSH, so it appears that my Thyroid is "following orders" from my Pituitary, I just think I have an abnormally high amout of FT3 compared to FT4 for not being on any medications).

Which of the following sounds like the most likely cause?
  • Low Serum Ferritin (6 NG/ML - Range: 25-335)
  • Primary Adrenal Insufficiency (High ACTH, low-normal Cortisol, low and "flattened" 24-h saliva rhythm)
  • High Estradiol (I heard that Estradiol and T3 both compete for the same receptors - is that true?)
  • Low Testosterone with a low LH and FSH (may just be Secondary to high Estradiol)
  • My body is just really good at turning T4 into T3...

Last edited by TheAntiEndo; 04-21-2008 at 02:43 PM.

 
Old 04-22-2008, 09:22 AM   #2
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Re: Can low Ferritin (or something else) block T3 binding and increase circulating T3

<BUMP Type="SHAMELESS">
Anyone?
</BUMP>

 
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Old 04-22-2008, 09:30 AM   #3
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Re: Can low Ferritin (or something else) block T3 binding and increase circulating T3

Well I fixed my B12 and ferritin.. working on the vit D deficiency.. and after addressing those and the thyroid.. my ACTH was high and cortisol flat.. low. Only fix for my low.. kaput adrenals was hydrocortisone supplementation in addition to my thyroid supplementation. I will see how my first 4 weeks on HC tabs adjusts the 40+&#37; difference in my T4 T3 levels.

So in my experience you are looking at this scenerio.
Primary Adrenal Insufficiency (High ACTH, low-normal Cortisol, low and "flattened" 24-h saliva rhythm)


MG
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