Re: Taking Synthroid At Night Instead Of Morning
Your stomach is never as empty at night as it is in the a.m. The main consideration is to get as much of the T4 from the tablet into your bloodstream as possible. If much of it is lost to excretion, there isn't as much there to convert. It's been proven that absorption of T4 from the tablet is as much as 80% from an empty stomach to as little as 40% when food is present in the gut. Besides that, it isn't an immediate conversion, anyway. T4 is stored on the carrier protein and circulates until conversion is needed. So the T4 that is converting better at night might just be the T4 you took a week ago, not what you took hours before.
Taking the med at night can be successful, but it depends whether you have an MD willing to give you the much larger dose that you're probably going to need. Many MDs have a limit they refuse to exceed.