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Old 04-28-2008, 12:37 PM   #1
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TSH Suppressed by T3

I hate to sound under educated, but well, I guess I am. Is it good that the TSH be suppressed while taking L-thyroxine? Or is this the outcome that you don't want?
What does it all mean? I really don't understand any of the info that I see about it. Could taking the l-thyroxine help symptoms that aren't really thyroid related and make others worse, would that be a sign that you need to stop?

Also heard that you can't stop taking synthroid once you have started? Why? and is it just that you can't stop taking it if you actually need it b/c the thyroid won't heal itself? Or is it really bad to stop?

Any info would help/

Thanks

 
Old 04-30-2008, 11:54 PM   #2
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Re: TSH Suppressed by T3

TSH usually doesn't become suppressed while taking thyroxine-only (T4) meds. It is usually suppressed when a T3 med is added to the T4. It isn't necessarily good or bad that TSH is suppressed, except in the case of thyroid cancer survivors; their TSH must be suppressed in order to prevent recurrence.

The reason that TSH doesn't matter for the rest of us is because it isn't a thyroid hormone. It's a pituitary hormone, and its only function is to signal the thyroid gland to increase or reduce its own output of hormone. It doesn't create or relieve symptoms of any sort. The thyroid hormones are the ones that regulate cellular metabolism, and the ones that create symptoms when their levels are off kilter. As long as the free thyroid hormone levels don't exceed about 80% of their ranges, there is no danger in suppressing the TSH. Just don't expect most mainstream MDs to understand that. Some do, though, and their patients are more likely to receive dosages of thyroid hormone that will enable them to regain their health.

Supplements of thyroid hormones will in no way affect symptoms that are not being caused by lack of it. If a symptom is caused by low thyroid, it will disappear when the proper dose is provided; but if it's caused by something else, all the hormone in the world won't fix it.

It's a bit of a myth that once hormone is taken that it can't be stopped. When the med is stopped, the gland will start working again, if it's able to. It's just that most cases of hypoT are caused by autoimmune destruction of the gland, and that damage doesn't allow for it to start working again. When the gland has been irreversibly damaged, hormone must be taken for life.

 
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Old 05-01-2008, 02:34 AM   #3
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Re: TSH Suppressed by T3

Quote:
Originally Posted by midwest1 View Post
TSH usually doesn't become suppressed while taking thyroxine-only (T4) meds. It is usually suppressed when a T3 med is added to the T4. It isn't necessarily good or bad that TSH is suppressed, except in the case of thyroid cancer survivors; their TSH must be suppressed in order to prevent recurrence.

............ The thyroid hormones are the ones that regulate cellular metabolism, and the ones that create symptoms when their levels are off kilter.

As long as the free thyroid hormone levels don't exceed about 80% of their ranges, there is no danger in suppressing the TSH.

Just don't expect most mainstream MDs to understand that.

Some do, though, and their patients are more likely to receive dosages of thyroid hormone that will enable them to regain their health.

........... It's just that most cases of hypoT are caused by autoimmune destruction of the gland, and that damage doesn't allow for it to start working again. When the gland has been irreversibly damaged, hormone must be taken for life.
Re AUTO-IMMUNE destruction of the thyroid.....You mean allergy?

Allergy testing showed "OWN BACTERIA" on the list, so, are you saying this is why I've progressed to Levothyroxine 300, over (in my 70's, proud to have survived, and diabetic) over a lifetime?

I've been doing well on that dosage for about 5 yrs, and don't want to go any higher, unless I get really worse. Is that likely? Why am I stabilized if it's allergy? Because I take a lot of allergy pills now?

Labs in my area haven't been updating their forms since before 2000, that I know of, there's been so many changes nationwide in the "range", except one where I know the girl that runs it and she knows all about "Third Generation" TSH testing, says the lower figure is now 0.27. I'm in SE Michigan. Is this true nationwide?

I googled "3rd GenerationTSH", testing, still not sure I understand. Will you briefly and simply address that while not forgetting my other questions? Good post, lots of info there. TIA. Eagle

Editing to add, because my old B.C. card was going to be replaced soon, I stopped in at one of those places where you don't have to have an appointment to get a Pap test, and thought of a new way of testing doctors in advance about thyroid, we've all had to try so many, an expensive and time-consuming endeavor.

I asked him what's the TSH range at the lab he uses. He said "below 5" so I knew he doesn't know a thing about thyroid. Do you all agree that's a good shortcut test? I'm planning to use it again.

Some doctors have just said they only studied thyroid about 10 minutes in med school and that all they know is that you give 1 gr of Synthroid, to start out with. Members here have pointed out new patients start with less and only increase gradually, so even that was wrong. They don't seem expect patients to have studied the subject online like this, and to have learned a lot as they should have, not only from the internet but also from our long experience.

Don't forget my other questions, please. You're good at this.

Last edited by Eagle; 05-01-2008 at 02:54 AM.

 
Old 05-01-2008, 06:47 AM   #4
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Re: TSH Suppressed by T3

[url]http://www.healthboards.com/boards/showthread.php?t=597479[/url]
It goes into autoimmune Hashimoto's thyroiditis and a lot more...

There is a thorough post on T3, T4 and other factors that can surpress TSH and why.

It also has a detailed post on normal TSH with the supporting articles. Normal TSH is now less than 2.5.

Eagle,
No not an allergic destruction of your thyroid exactly. Autoimmune is where your own immune system is trigger in such a way that you make.. humm.. specialized antibodies.. like thyroid seeking white blood cells.. that seek out and attack your thyroid. Antihistamines.. allergy pills just stop your histamine receptors from producing histamine.

Increased demand in T4 may be due to an increasing tolerance to the medication.. where your body is not liking that formulation and rejecting it.. thus you have to take more. You can test how well your body is binding the T4 with a TBG test.

TSH 3rd Gen range is 0.3-2.5 now.. labs may not be up to date.. the MD may know this and adjust mentally ignoring the range.. then again maybe not. As too slight shifts in the range. It is possible you have a lower limit of 0.27. Each instrument is calibrated to optimal precision and accuracy.. this will float the ranges a bit.. but they should be close to the 0.3 - 3.0.

How I find out about MDs is I call and ask about testing policies and such. Just because a lab is behind doesn't mean the MD using them is... In many cases it does.. but hey! There might be an odd upto date MD in the mix. Most MDs only get a brief introduction into other specialized fields and the specialist.. well even they do not keep up. You just have to do you own leg work and ride them hard til you get where you want to be.

MG
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Last edited by mkgbrook; 05-02-2008 at 05:25 AM.

 
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Old 05-01-2008, 07:29 AM   #5
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Re: TSH Suppressed by T3

"TSH third generation" is simply the "edition" of the test, so to speak. Third generation is the newest, I think. Then there's "sensitive" and "ultrasensitive". None of that is too important, really. None of the versions of TSH test is any great shakes when it comes to thyroid treatment. There's so much more to it... and a good doctor knows that.

Your method for testing a doctor could be made better by asking a followup question: "The lab range ends at 5, but what level do you consider to be suspect for hypothyroidism?" Many MDs don't strictly adhere to and follow the lab ranges as gospel, anyway. Lucky for us!

Last edited by midwest1; 05-01-2008 at 07:32 AM.

 
Old 05-02-2008, 03:28 AM   #6
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Thanks to Both of You!

I think I'll print this out in case I need to convince some doctor that the range norm has changed a lot since 2000, and potencies have changed also, and that online forum people often point out the discrepancy problem.

Thanks to both of you. Very helpful. I had done a search to define the "3rd Generation" test, and you guys' definition is better. (And, Midwest, you're not the same Midwest who's in a music notation forum, are you? I'm getting from a friend an old copy of Encore's lower-end program they don't sell any more, to see if it will do long cadenza's as tuplets, which I've done with PrintMusic but they're not evenly spaced notes. I know, read again how to space them individually. I've had to adjust the beaming a lot. It was an awful lot of work to get them in as 32nd notes instead of 16ths, planning to convert them back to 16ths. Hope it's okay to ask here if you're that same person who gives good advice there also.)

 
Old 05-02-2008, 09:19 AM   #7
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Re: TSH Suppressed by T3

thanks ladies for helping me to understand this. It is all so mind boggling, I dont know how you can keep it all straight in your heads, I'll forget this and have to reread every time I think about it.

When this all started, my levels were "normal" and my tsh was slightly hypo? I went to my famiy dr monday and asked her all of this. She is so willing to do what ever I want, which is great, but I don't know what I want or what I am trying to do. My Thyroid was almost 3 times the size that it should be, says endo, so maybe that is why the suppression of T3, but I can't be sure. He is 3.5 hours away and with gas prices, I just want to stay close to home. BUT.........I am so glad to have this site with such knowledgeable women~!.

Thanks to all of you. I will be doing a complete hormone work up in June so hopefully it sheds some light on my situation.

Dawn

 
Old 05-03-2008, 08:37 AM   #8
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Wink To Eagle, new to site.

Hi Eagle, this is Katanya, I am also in a south suburb of Detroit. I am 44 years old. Do you know of any endocrinologists, acupuncturists, etc. that treat advanced age related fertilty issues. My fsh has always been low, sometimes as low as 2.5, although recently it rose. I would appreciate any info you have. Also I just had my thyroid tested too.


Susanne




Quote:
Originally Posted by Eagle View Post
I think I'll print this out in case I need to convince some doctor that the range norm has changed a lot since 2000, and potencies have changed also, and that online forum people often point out the discrepancy problem.

Thanks to both of you. Very helpful. I had done a search to define the "3rd Generation" test, and you guys' definition is better. (And, Midwest, you're not the same Midwest who's in a music notation forum, are you? I'm getting from a friend an old copy of Encore's lower-end program they don't sell any more, to see if it will do long cadenza's as tuplets, which I've done with PrintMusic but they're not evenly spaced notes. I know, read again how to space them individually. I've had to adjust the beaming a lot. It was an awful lot of work to get them in as 32nd notes instead of 16ths, planning to convert them back to 16ths. Hope it's okay to ask here if you're that same person who gives good advice there also.)

 
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