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Old 10-01-2008, 04:15 PM   #1
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tygwyn HB User
Hashimotos/Hypo and Miscarriage

Prior to being diagnosed with thyroid disease (multi nodular goiter which was removed and then found to be in a background of hashimotos) I suffered 6 miscarriages...all in the early stages thankfully but still hard all the same.

I'm lucky enough to have one daughter who is 8 - one miscarriage was before her and 5 afterwards. We would love to have another child but we dont want to put ourselves through another miscarriage.

Two Endos I spoke to and a fertility specialist (she ran some other tests and all looked good apparently) didnt link the miscarriages to my thyroid disease, but a new Endo I spoke to and my new GP have linked it. The Endo mentioned that it wasnt a direct link to Hashimotos, but more of a link to autoimmune diseases...but the GP seemed to link it directly to Hashimotos and believed that now I no longer had a thyroid, and was receiving treatment, my next pregnancy would run smoothly! It was a bit of a flippant answer though to be honest and she really didnt ask too many questions about my personal situation so I take that answer with a pinch of salt - although obviously I would love her to be right.

I am still not stabalised on meds so wouldnt think about trying again until I am, but I'd like to hear anyones opinion on this if you have one.
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Rach xxxx

Total Thyroidectomy Oct 06 due to Massive Multi Nodular Goiter and Hashi
Adrenal Fatigue
180mg NTH
28mg HC
2 x Caltrate

Rach xxxx

 
Old 10-01-2008, 07:33 PM   #2
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mkgbrook HB Usermkgbrook HB Usermkgbrook HB Usermkgbrook HB Usermkgbrook HB Usermkgbrook HB Usermkgbrook HB Usermkgbrook HB Usermkgbrook HB Usermkgbrook HB Usermkgbrook HB User
Re: Hashimotos/Hypo and Miscarriage

I had two Endos, a high risk OB, and an MFM explain the mechanism for Hashimoto's attack on a fetus to me. Their explanation as I interpret it is that in patients with Graves and Hashimoto's the antibodies of the mother cross the placenta barrier and attack the thyroid of the child. This occurs when the mother is not balanced in thyroid levels or monitored properly. The increased risk of miscarriage results from damage caused by thyroid attack on the developing fetus. Hashimoto's tends to be worse than Graves initially because there is too little hormone for proper development.

In the first 12 weeks fundamental systems are developing if ones antibodies are not under control and there is not enough T4 for the developing infant than the fetus may not develop properly and be rejected by your body. Increased antibodies with adequate levels of T4 should allow for proper development, while the developing fetus must be monitored for the development of nodules and thyroid growth with frequent targeted ultrasound and test for hypothyroidism upon delivery. In the case of Graves antibodies you have to fight hyperthyroid issues in the child and they add other complications later in pregnancy.

I have not had a miscarriage that I know of I have only been pregnant once after being told I was infertile. The pregnancy was rough on me, but my child came out fine. He was a 10 lb premie. Big boy. I am at a high risk now because my antibody levels climbed above 1000 and my T4 levels are in the out house. I am using selenium in an attempt to lower my antibody levels and treating my hypoadrenalism, hypoglycemia, AND Hashimoto's and Graves. I am following my MFM's advice get my T4 levels above 50%, get my TPOAb's and TGAb's as low as I can and then go for it. As soon as I suspect pregnancy get my FT levels checked and up my T4 intake and test FTs every 2-4 weeks and adjust accordingly. Targeted ultrasounds will be performed ever 8 weeks. I posted a thread after talking with my MFM and Obs. I will dig it up for you in case you are interested.

[url]http://www.healthboards.com/boards/showthread.php?t=585150[/url]

So I can not say what was the cause. Some other stat's on pregnancy in general: only 25% of pregnancies actually take, only 25 % of multiple pregnancies result in a multiple birth with extra fetal matter being reabsorbed to strengthen the remaining fetus. I found out that left handedness is suspected to be the result of the survival of the mirror image identical twin. Having an Ob in the family WHO loves to teach and research gets me all sorts of neat information. Most miscarriages occur before we know it. They are often mistaken as missed/late with a heavy period. I have had a few of those. Finally if a hypothyroid patient gets their T4 levels in the 60-80% range of normal the chances for cognitive dysfunction in the developing fetus is no greater than that of a woman with a normal functioning thyroid. Women with antibodies are at a higher risk for miscarriages, but my SIL OB and MFM and high risk OB have had HUNDREDS of patients with Hashimoto's deliver happy healthy babies. My SIL reminded me of that last night. One can not give up hope, what will be will be.

I can only wish you the best of luck. My husband and I started fighting for treatment of my Hashi's in a pursuit of trying to conceive or second child. Now I have MANY conditions to deal with and we as still not ready. However we are not giving up. We will race the proverbial clock. If I hit 35 before my levels are stable, then a second child was not meant for me. You can only do your best to prepare yourself and then go with your gut and heart to determine if you are ready to take the risks. In the mean time I bless my lucky stars for my son and will do the best by him I can.

MG
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If we learn by our mistakes, I am working on one hell of an education.

Last edited by mkgbrook; 10-02-2008 at 06:23 AM. Reason: Spelling

 
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Old 10-02-2008, 04:51 AM   #3
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mmmcoffee HB User
Re: Hashimotos/Hypo and Miscarriage

I too, had a miscarriage that was only 10 wks into the pregnancy. We had been told I'd never have kids and did go thru fertility treatments about 13 yrs ago. We ended up adopting our 2 girls. My Hashi's, goiter and multiple nodules has probably been here for years, but never diagnosed because I hadn't been to a Dr in ages. Looking back at old pictures, my neck has been 'full' for years. My Endo did say that not treating the Hashi's could raise the risk of miscarriage. Well, I guess it did in my case. Now, I've had a TT and next is RAI. We are not going to try to get pregnant again. One miscarriage was hard enough, I couldn't imagine going thru 6 of them. Good luck to you. I would think once your meds are set your risk would be alot lower. Again, we wish you the best of luck.

mmmcoffee

 
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